Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC CBL0137 hydrochloride | 1197397-89-9 | 99.7% | 372.89 | 1 ML
Supplier: Medchemexpress LLC HY18935A10MM/1ML
CBL0137, a curaxin compound, is a histone chaperone that facilitates chromatin transcription (FACT) inhibitor. It downregulates NF-κB, activates p53, and restores both histone H3 acetylation and trimethylation. CBL0137 acts as an anticancer agent by inducing cancer cell apoptosis. It is intended for research use only and not for sale to patients.
- Histone chaperone FACT inhibitor.
- Downregulates NF-κB and activates p53.
- Restores histone H3 acetylation and trimethylation.
- Induces cancer cell apoptosis.
- Efficacious in preclinical glioblastoma models.
- Reduces colony formation with Gemcitabine in pancreatic cancer cells.
- Modulates RRM1 and RRM2 gene expression.
- Suppresses tumor growth in various xenografts.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?