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Medchemexpress LLC CBL0137 hydrochloride | 1197397-89-9 | 99.7% | 372.89 | 1 ML
SDP

Catalog No. 5000385237
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CBL0137, a curaxin compound, is a histone chaperone that facilitates chromatin transcription (FACT) inhibitor. It downregulates NF-κB, activates p53, and restores both histone H3 acetylation and trimethylation. CBL0137 acts as an anticancer agent by inducing cancer cell apoptosis. It is intended for research use only and not for sale to patients.

  • Histone chaperone FACT inhibitor.
  • Downregulates NF-κB and activates p53.
  • Restores histone H3 acetylation and trimethylation.
  • Induces cancer cell apoptosis.
  • Efficacious in preclinical glioblastoma models.
  • Reduces colony formation with Gemcitabine in pancreatic cancer cells.
  • Modulates RRM1 and RRM2 gene expression.
  • Suppresses tumor growth in various xenografts.

Catalog No. 50-003-85237 Supplier Medchemexpress LLC Supplier No. HY18935A10MM/1ML
May include imposed supplier surcharges.
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CBL0137, a curaxin compound, is a histone chaperone that facilitates chromatin transcription (FACT) inhibitor. It downregulates NF-κB, activates p53, and restores both histone H3 acetylation and trimethylation. CBL0137 acts as an anticancer agent by inducing cancer cell apoptosis. It is intended for research use only and not for sale to patients.

  • Histone chaperone FACT inhibitor.
  • Downregulates NF-κB and activates p53.
  • Restores histone H3 acetylation and trimethylation.
  • Induces cancer cell apoptosis.
  • Efficacious in preclinical glioblastoma models.
  • Reduces colony formation with Gemcitabine in pancreatic cancer cells.
  • Modulates RRM1 and RRM2 gene expression.
  • Suppresses tumor growth in various xenografts.

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