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Medchemexpress LLC CBL0137 hydrochloride | 1197397-89-9 | 99.7% | 372.89 g/mol | C21H25ClN2O2 | 10 MG
Supplier: Medchemexpress LLC HY18935A10MG
CBL0137 hydrochloride is a research-grade small molecule that inhibits the histone chaperone FACT, activates p53, and suppresses NF-κB signaling. It is used in preclinical studies to probe chromatin regulation and anticancer mechanisms in cell-based and biochemical assays.
- Inhibits the histone chaperone FACT.
- Activates p53 in cell-based assays (IC50 ≈ 0.37 μM).
- Inhibits NF-κB signaling in cell-based assays (IC50 ≈ 0.47 μM).
- High chemical purity, typically reported as 99.7%.
- Available as solid packs and as a DMSO solution for in vitro use.
- Suitable for mechanistic studies, pathway modulation, and preclinical cancer research.
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