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AdipoGen CBP ms Hishighly active
SDP

Supplier:  AdipoGen AG40T0016C002

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Protein. Mouse full-length CREB-binding protein fused at the C-terminus to a His-tag. Source Sf21 cells. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50-100mM imidazole and 10% glycerol. Purity >95% SDS-PAGE. CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.

Catalog No. 50-256-2795


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