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Medchemexpress LLC CC260 | 2411088-26-9 | 99.5% | 490.43 | 100 MG
Supplier: Medchemexpress LLC HY139188100MG
CC260 is a selective PI5P4Kα and PI5P4Kβ inhibitor with Ki values of 40 nM and 30 nM, respectively. It does not inhibit or only weakly inhibits other protein kinases like Plk1 and RSK2. CC260 is suitable for research in cell energy metabolism, diabetes, and cancer.
- Enhances insulin-induced Akt phosphorylation at both Thr-308 and Ser-473
- Suppresses S6K phosphorylation (Thr-389) by mTORC1
- Significantly increases phosphorylation of acetyl-CoA carboxylase (ACC) in a dose-dependent manner
- Reduces the ability of BT474 cells to survive serum starvation
- Increases glycolytic ATP production in BT474 cells
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