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Apexbio Technology LLC CCCP,500mg CAS# 555-60-2
Supplier: Apexbio Technology LLC B5003500
CCCP (carbonyl cyanide m-chlorophenyl hydrazine) is widely used uncoupler of oxidative phosphorylation.The uncoupler of oxidative phosphorylation blocks ATP synthesis by collapsing the proton motive force.In vitro: A genetic β-galactoside reporter system with a disk diffusion assay on MacConkey Lactose agar petri plates to monitor maintenance of the bacteriophage λ prophage state and viral induction in Escherichia coli K-12. It presented evidence that the phage λ major lytic promoters, pL and pR, are activated via cells containing the reporters following exposure to the energy poison CCCP. Requirement of expression of the λ lytic promoters in response to CCCP is host RecA function and an auto-cleavable CI repressor, as does SOS induction of the λ prophage occurring by a DNA damage-dependent pathway. CCCP-mediated activation of the λ lytic promoters required λ Cro function. CCCP does not modulate an sfi-lacZ SOS reporter [1]. Other sizes are also available. Please inqury us for quote.
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