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Abcam CCT 018159, Hsp90 ATPase inhibitor, 10MG

Supplier:  Abcam AB14641210MG

Encompass_Preferred

MW 352.39 g/mol, Purity >98%. Selective, cell-permeable Hsp90 ATPase inhibitor (IC₅₀ values are 3.2 μM and 6.6 μM for Human Hsp90 beta and yeast Hsp90 respectively). Exhibits no detectable effects against Human Hsp72 ATPase or topoisomerase II. Shows antiproliferative effects. Upregulates Hsp72 and downregulates c-Raf and cdk4. Antitumor activity is independent of NQO1/DT-diaphorase and P-glycoprotein expression.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-4641


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