Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC CCT007093 176957-55-4 10mg
Supplier: Apexbio Technology LLC B327410
CCT007093 (CAS 176957-55-4) is a small-molecule inhibitor targeting PPM1D a protein phosphatase involved in cellular stress response pathways It is a thienylidene cyclopentanone derivative that exhibits inhibitory activity against PPM1D with an IC50 of 8 4 M in vitro using recombinant phosphorylated p38 as a substrate In cellular assays CCT007093 selectively reduces viability in MCF-7 cells compared to HeLa cells decreasing cell viability by 40% after two days The compound induces cell death in a p38 kinase-dependent manner and increases p38 phosphorylation an effect reversible by the p38 inhibitor SB203580 CCT007093 is used in research on PPM1D function and in studies of stress signaling and targeted cell death
This item is not returnable.
View return policy
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?