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Apexbio Technology LLC CCT007093 176957-55-4 10mg
SDP

Catalog No. 502240598
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CCT007093 (CAS 176957-55-4) is a small-molecule inhibitor targeting PPM1D a protein phosphatase involved in cellular stress response pathways It is a thienylidene cyclopentanone derivative that exhibits inhibitory activity against PPM1D with an IC50 of 8 4 M in vitro using recombinant phosphorylated p38 as a substrate In cellular assays CCT007093 selectively reduces viability in MCF-7 cells compared to HeLa cells decreasing cell viability by 40% after two days The compound induces cell death in a p38 kinase-dependent manner and increases p38 phosphorylation an effect reversible by the p38 inhibitor SB203580 CCT007093 is used in research on PPM1D function and in studies of stress signaling and targeted cell death

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Catalog No. 50-224-0598 Supplier Apexbio Technology LLC Supplier No. B327410
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CCT007093 (CAS 176957-55-4) is a small-molecule inhibitor targeting PPM1D a protein phosphatase involved in cellular stress response pathways It is a thienylidene cyclopentanone derivative that exhibits inhibitory activity against PPM1D with an IC50 of 8 4 M in vitro using recombinant phosphorylated p38 as a substrate In cellular assays CCT007093 selectively reduces viability in MCF-7 cells compared to HeLa cells decreasing cell viability by 40% after two days The compound induces cell death in a p38 kinase-dependent manner and increases p38 phosphorylation an effect reversible by the p38 inhibitor SB203580 CCT007093 is used in research on PPM1D function and in studies of stress signaling and targeted cell death

This item is not returnable. View return policy
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