Medchemexpress LLC CCT367766 (formic) | 98.1% | 992.42 | 100 MG

Supplier:  Medchemexpress LLC HY122653A100MG

CCT367766 formic is a potent, third-generation heterobifunctional and Cereblon-based pirin targeting protein degradation probe (PDP, or PROTAC). It depletes pirin protein expression at low concentrations. CCT367766 formic shows a moderate affinity for the CRBN-DDB1 complex with an IC50 value of 490 nM. It also reveals a good affinity for recombinant pirin and CRBN with Kd values of 55 nM and 120 nM, respectively. This compound provides a potential chemical tool to study a largely unexplored protein.

• Depletes pirin protein expression at low concentrations.
• Moderate affinity for CRBN-DDB1 complex with an IC50 value of 490 nM.
• Good affinity for recombinant pirin and CRBN with Kd values of 55 nM and 120 nM.
• Potential chemical tool for studying largely unexplored proteins.

Catalog No. 50-004-36785