Medchemexpress LLC CCT367766 (formic) | 98.1% | 992.42 | 50 MG

Supplier:  Medchemexpress LLC HY122653A50MG

CCT367766 formic is a potent third-generation heterobifunctional and Cereblon-based pirin targeting protein degradation probe. This PROTAC effectively depletes pirin protein expression at low concentrations. It demonstrates a moderate affinity for the CRBN-DDB1 complex with an IC50 of 490 nM. Furthermore, it shows good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. This product serves as a valuable chemical tool for researching a protein that is currently not well understood.

• Potent third-generation PROTAC.
• Targets pirin protein degradation.
• Moderate affinity for the CRBN-DDB1 complex (IC50 = 490 nM).
• Good affinity for recombinant pirin (Kd = 55 nM) and CRBN (Kd = 120 nM).
• Useful chemical tool for pirin protein studies.

Catalog No. 50-004-38697