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CD11a (LFA-1A) Mouse, anti-Human, RB780, Clone: HI111, BD Horizon™

Catalog No. BDB568776 Shop All BD Biosciences Products
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BDB568776 100 Tests
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Description

Mouse Monoclonal Antibody

The HI111 monoclonal antibody specifically binds to CD11a, the 180 kDa integrin α chain. This type I transmembrane glycoprotein associates with CD18 (integrin β2) to form the heterodimeric glycoprotein CD11a/CD18. This heterodimer is also known as the lymphocyte (leukocytes) function associated antigen-1 (LFA-1) that is expressed on all leukocytes. LFA-1 is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50).

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11a (LFA-1A)
Applications Flow Cytometry
Clone HI111
Conjugate RB780
Formulation Aqueous buffered solution containing ≤0.09% sodium azide
Host Species Mouse
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Secondary
Gene ID (Entrez) 3683
Target Species Human
Content And Storage Refrigerate (2°C to 8°C)
Isotype IgG1 κ
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