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AdipoGen CD137 mouseFc h rec
Supplier: AdipoGen AG40A0025C050
Protein. The extracellular domain of mouse CD137 aa 1-185 is fused at the C-terminus to the Fc portion of human IgG1. Source HEK 293 cells. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm filtered solution in PBS. Purity >95% SDS-PAGE. CD137 4-1BB is a member of the tumor necrosis factor TNF receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.
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