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AdipoGen CD137L Soluble ms rec

Supplier: AdipoGen AG40A0020YC050
Protein. The extracellular domain of mouse CD137L aa 104-309 is fused at the N-terminus to a FLAG -tag. Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Binds to mouse CD137. Purity >95% SDS-PAGE. The CD137 ligand CD137L 4-1BBL is a member of the tumor necrosis factor TNF family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 TRAF1 and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
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