Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Secondary Antibodies
  5. Mouse Secondary Antibodies
  6. CD25 (IL-2 Receptor α) Mouse, anti-Human, RB780, Clone: 2A3, BD Horizon™

CD25 (IL-2 Receptor α) Mouse, anti-Human, RB780, Clone: 2A3, BD Horizon™

Catalog No. BDB568689 Shop All BD Biosciences Products
Change view
Click to view available options
Quantity:
100 Tests
25 Tests
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
BDB568689 25 Tests
BDB568688 100 Tests
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. BDB568689 Supplier BD Biosciences Supplier No. 568689
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

The 2A3 monoclonal antibody specifically binds to human CD25, the low-affinity alpha subunit of the Interleukin-2 Receptor (IL- 2Rα). CD25 associates with CD122 (IL-2Rβ chain) and CD132 (common γ chain or γc) to form the high-affinity signal-transducing IL-2R complex. CD25 is expressed by subsets of thymocytes and peripheral blood lymphocytes including CD4+CD25+ regulatory T cells and memory T cells. CD25 antigen density increases on activated T cells including phytohemagglutinin (PHA)-, concanavalin A (Con A)-, and CD3-activated T lymphocytes. High levels of CD25 can be expressed by T lymphocytes from mixed lymphocyte cultures and by human T-lymphocyte leukemia virus (HTLV)-infected T-lymphocyte leukemia lines, for example, HUT-102. CD25 can also be expressed by activated B cells and macrophages. Recombinant IL-2 blocks the binding of the 2A3 antibody to PHA-activated T lymphocytes.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD25 (IL-2 Receptor α)
Applications Flow Cytometry
Clone 2A3
Conjugate RB780
Formulation Aqueous buffered solution containing ≤0.09% sodium azide
Host Species Mouse
Immunogen Human Phytohemagglutinin-activated T Cells
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Secondary
Gene ID (Entrez) 3559
Target Species Human
Content And Storage Refrigerate (2°C to 8°C)
Isotype IgG1 κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.