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  6. CD3 Mouse, anti-Human, RB780, Clone: UCHT1 (also known as UCHT-1; UCHT 1), BD Horizon™

CD3 Mouse, anti-Human, RB780, Clone: UCHT1 (also known as UCHT-1; UCHT 1), BD Horizon™

Catalog No. BDB568679 Shop All BD Biosciences Products
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25 Tests
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BDB568678 100 Tests
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Description

Mouse Monoclonal Antibody

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD3
Applications Flow Cytometry
Clone UCHT1 (also known as UCHT-1; UCHT 1)
Conjugate RB780
Formulation Aqueous buffered solution containing ≤0.09% sodium azide
Host Species Mouse
Immunogen Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Secondary
Gene ID (Entrez) 916
Target Species Human
Content And Storage Refrigerate (2°C to 8°C)
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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