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Genscript Corporation CD30/TNFRSF8 hFc Chimera Huma
Supplier: Genscript Corporation Z04187500
The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153 TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions CD30 expression is upregulated in various hematological malignancies including Reed-Sternberg cells in Hodgkin s disease (HD) anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin s lymphomas (NHLs)
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