Human CD300LG, also known as Nepmucin, is a member of the CD300 family of proteins containing an Ig-like V-type domain. It is highly expressed in human heart, skeletal muscle, and placental tissues and functions as a receptor that may mediate L-selectin-dependent lymphocyte rolling. This protein binds to lymphocytes and SELL in a calcium-dependent manner. Produced in HEK293 cells, this protein is provided in a lyophilized powder form and includes a C-terminal polyhistidine tag.
- Expressed in human HEK293 cells
- Contains one Ig-like V-type domain
- Purity >90% as determined by SDS-PAGE
- Calculated molecular weight of 25.6 kDa; migrates as 33-68 kDa under reducing conditions
- Endotoxin levels <1.0 EU per μg
- Formulated in PBS, pH 7.4, with trehalose as a protectant