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  6. CD326 (Ep-CAM) Rat, anti-Mouse, RB780, Clone: G8.8, BD Horizon™

CD326 (Ep-CAM) Rat, anti-Mouse, RB780, Clone: G8.8, BD Horizon™

Catalog No. BDB568737 Shop All BD Biosciences Products
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25 μg
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BDB568737 25 μg
BDB568736 0.1 mg
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Description

Rat Monoclonal Antibody

The G8.8 monoclonal antibody recognizes CD326/Ep-CAM (Epithelial Cell Adhesion Molecule), also known as gp40 in the mouse and by a variety of names (including GA733-2, CO17-1A, and EGP) in the human. In the mouse, Ep-CAM is a 40-42 kDa cell-surface type 1 transmembrane glycoprotein expressed on thymic epithelial cells, thymic dendritic cells, immature thymocytes, a small subset of peripheral T lymphocytes, intestinal epithelium, kidney-collecting tubule epithelium, keratinocytes, Langerhans cells and lymph node and splenic dendritic cells. Profiles of Ep-CAM expression on fetal thymocytes and on the CD4[-] CD8[-], CD4[+] CD8[+], CD4[-] CD8[+], and CD4[+] CD8[-] subsets of adult thymocytes have been published. In unrelated studies, mouse Ep-CAM mRNA was detected in tissues containing epithelial cells (kidney, stomach, intestine, lung, and thymus) and in plasma cells and plasmacytomas, but not in heart, muscle, liver, brain, spleen, B lymphomas, or pre-B lymphomas. Ep-CAM is a Ca[2+] independent homophilic adhesion molecule that is proposed to play roles in the development and normal function of epithelial tissues and in the progression of carcinomas.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD326 (Ep-CAM)
Applications Flow Cytometry
Clone G8.8
Concentration 0.2 mg/mL
Conjugate RB780
Formulation Aqueous buffered solution containing ≤0.09% sodium azide
Host Species Rat
Immunogen Glycoconjugates from BALB/c mouse-derived TE-71 medullary thymic epithelial cell line
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Secondary
Gene ID (Entrez) 17075
Target Species Mouse
Content And Storage Refrigerate (2°C to 8°C)
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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