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Genscript Corporation CD37 hFc Chimera Human
Supplier: Genscript Corporation Z04199500

CD37 is a tetraspanin expressed prominently on the surface of B cells It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia Currently several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials Given the unique role of CD37 in the biology of B cells it seems that CD37 constitutes more than a docking point for monoclonal antibodies and targeting this molecule may provide additional benefit to relapsed or refractory patients
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