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Medchemexpress LLC CD40L/CD154/TRAP Mo 500ug

Supplier: Medchemexpress LLC HYP72908500UG
CD40L (CD154 TRAP) is a ligand to CD40/TNFRSF5 acts function by generating a costimulatory signal that up-regulates IL-4 synthesis[1] CD40L is specifically expressed on activated CD4 T-lymphocytes and involves in activation of NF- B/MAPK pathway[2][3] CD40L also involves in B cell differentiation maturation and apoptosis[4] CD40L in mouse cleaved into 2 chains of membrane form (1-260 a a ) and soluble form (112-260 a a ) which serves as a ligand for integrins (ITGA5 ITGB1 and ITGAV ITGB3) CD40L/CD154/TRAP Protein Mouse (HEK293 Fc) is expressed in HEK392 cells with N-terminal hFc-tag
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