Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
AdipoGen CD40L (human) ELISA Kit (96 wells)
Supplier: AdipoGen AG45B0018KI01
ELISA Assay. Detects soluble human CD40L in serum, plasma and cell culture supernatant. Colorimetric sandwich assay. Sample types: Cell Culture Supernatant, Plasma, Serum. Range: 0.015625 to 1ng/ml. Sensitivity: 10pg/ml. Defective expression of CD40L in humans leads to an inability to produce isotypes other than IgM (hyper IgM syndrome) and to an absence of germinal centers. In dendritic cells, CD40 ligation induces more effective antigen, enhances T-cell stimulatory capacity and induces production of several inflammatory cytokines and chemokines. CD40-CD40L interactions are crucially involved in development of autoimmune disease and have also impact on growth regulation of certain carcinomas. Elevated levels of sCD40L have been observed in sera from patients with systemic lupus erythematosus (SLE), chronic lymphocytic leukemia (CLL) and unstable angina.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?