Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
AdipoGen CD40L ms multimeric Biot
Supplier: AdipoGen AG40B0020BC010
Recombinant protein. Mouse CD40L aa 115-260 is fused at the N-terminus to mouse ACRP30headless aa 18-111 and a FLAG -tag. Binds to human and mouse CD40. Endotoxin <0.05EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. The costimulatory molecule CD40, a member of the tumor necrosis factor TNF receptor superfamily, critically regulates B cell and T cell function in adaptive immunity and inflammation by interacting with CD40L CD154. CD40L mediates a range of activities on B cells, including induction of activation-associated surface antigen, entry into cell cycle, isotype switching, immunoglobulin secretion and memory generation. CD40-CD40L interaction also plays important roles in monocyte activation and DC maturation. MultimericCD40L™ is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L in vivo.
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction