Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

STEMCELL Technologies CD437, Size: 5 mg
SDP

Supplier:  STEMCELL Technologies 72722

Encompass_Preferred

CD437 is the prototypical adamantyl arotinoid of the retinoid-related molecule family that acts as a selective agonist of retinoic acid receptor (RAR)γ (Kd = 6.5 µM, 2.5 µM, and 77 nM for RARα, β, and γ, respectively; Bernard et al.; Pérez-Rodríguez et al.). REPROGRAMMING· Increases speed and number of pre-induced pluripotent stem (iPS) cell colonies generated from mouse embryonic fibroblasts (MEFs) transfected with Oct4, Sox2, c-Myc, and Klf4 (Wang et al.).CANCER RESEARCH· Induces cell cycle arrest and apoptosis in a variety of cancer cells (Fontana and Rishi; Jin et al.; Li et al.; Valli et al.)· Decreases mRNA expression of squamous differentiation markers cytokeratin 1, involucrin, and SPR1 in the human head and neck squamous cell carcinoma cell line, UMSCC22B (Sun et al.).

Catalog No. 50-197-5968


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.