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Enzo Life Sciences CDK1/2 Inhibitor III (1mg). CAS: 443798-55-8
SDP

Supplier:  Enzo Life Sciences ALX270442M001

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Cell permeable triazolo-diamine compound that displays anti-proliferative properties in various human cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC50=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3β (IC50=32nM and 140nM). Alternative name: 5-Amino-3-((4-(aminosulfonyl)phenyl)amino)-N-(2,6-difluorophenyl)-1H-1,2,4-triazole-1-carbothioamide. Purity: ≥95% (HPLC). Appearance: White to off-white solid. Solubility: Soluble in DMSO (10mg/ml), tetrahydrofuran or acetone. Long Term Storage: -20°C.

Catalog No. 50-200-8564


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