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Medchemexpress LLC Cdk1/Cyc B-IN-1 | 2459916-56-2 | 98.5% | 353.85 | 50 MG

Supplier: Medchemexpress LLC HY14764650MG
CDK1/Cyc B-IN-1 (Compound 5) is a selective CDK1/Cyc B complex inhibitor with an IC50 of 97 nM. It triggers apoptosis and G2/M cell cycle arrest and demonstrates broad-spectrum cytotoxic action against cancer cell lines. In vitro, it is soluble in DMSO at 100 mg/mL.
- Induces apoptosis and G2/M cell cycle arrest
- Exhibits cytotoxic activity against HCT-116 cells (IC50 of 5.33 ± 0.69 μM)
- Exhibits cytotoxic activity against WI-38 cells (IC50 of 21.69 ± 1.04 μM)
- Shows antiproliferative activity against various human cancer cell lines
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