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Medchemexpress LLC CDK12-IN-E9 10mg | 2020052-55-3 | 434.53 | C24H30N6O2 | 10 MG
Supplier: Medchemexpress LLC HY117203A10MG
CDK12-IN-E9 is a research-grade small-molecule inhibitor that selectively and covalently inhibits cyclin-dependent kinase 12 (CDK12) and non-covalently inhibits CDK9. It is supplied as a solid for use in cellular and biochemical studies of transcriptional regulation and DNA damage response.
- Potent covalent CDK12 inhibition (IC50 23.9 nM).
- Non-covalent CDK9 activity (IC50 932 nM).
- High reported purity (~99.7%).
- Molecular weight 434.53 g/mol; formula C24H30N6O2.
- Soluble in DMSO (125 mg/mL with ultrasonic).
- Available in small research pack sizes suitable for early-stage experiments.
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