Invitrogen™ Human CDK16 (PCTK1)/cyclin Y, GST Tag Recombinant Protein

Catalog No.	Quantity
PV6381	1 mg
PV6379	10 μg
PV6380	100 μg

Catalog No. PV6381 Supplier Invitrogen™ Supplier No. PV6381

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Recombinant human CDK16 (107-end) and Cyclin Y (2-end) were co-expressed by baculovirus in Sf9 insect cells using N-terminal GST tags. , Validated in LanthaScreen™ Kinase Binding Assay, Protocols available for simple use and optimized performance, Multiple pack sizes available for convenient use Protein Form: Recombinant, Fragment The gene accession number for the two subunits (CDK16[PCTK1] and Cyclin y) are NP_006192.1 and NP_659449.3.

CDK16 (PCTK1)/cyclin Y belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. CDK16 plays a role in signal transduction cascades in terminally differentiated cells, in exocytosis, and in transport of secretory cargo from the endoplasmic reticulum. CDK16 is ubiquitously expressed with the highest levels detected in the brain and testis. CDK16 also contained the gene coding for ubiquitin-activating enzyme UBE1 that previously shown to mapped to Xp11.3.

Specifications

• Accession Number: Q00536, Q8ND76
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris HCl with 0.25mM DTT, 10mM glutathione, 150mM NaCl, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 219771, 5127
• Molecular Weight (g/mol): 71.1-65.5 kDa
• Name: Human CDK16 (PCTK1)/cyclin Y, GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 1 mg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: Cdk16; cdk16.L; cdk16.S; Cell division protein kinase 16; Crk5; cyclin dependent kinase 16; cyclin-dependent kinase 16; cyclin-dependent kinase 16 L homeolog; cyclin-dependent kinase 16 S homeolog; FLJ16665; PCTAIRE; PCTAIRE protein kinase 1; PCTAIRE1; PCTAIRE-1 protein kinase, alternatively spliced; PCTAIRE-motif protein kinase 1; pctgaire; pctk1; PCTK1 protein; Serine/threonine-protein kinase PCTAIRE-1; testis secretory sperm-binding protein Li 224 n
• Common Name: CDK16/Cyclin Y
• Gene Symbol: CCNY, CDK16
• Protein Length: aa 108-end, 2-end
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: 108-end; 2-end
• Content And Storage: Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol
  
  Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
• Kinase Group: Serine/Threonine Kinase
• Expression System: Baculovirus
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Fragment
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Drug Discovery: Signal Transduction