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Medchemexpress LLC CDK4/6-IN-15 (hydrochloride) | 99.0% | C21H28ClFN8S | 25 MG
Supplier: Medchemexpress LLC 25MGHY142076A
CDK4/6-IN-15 hydrochloride is an orally active and selective CDK4/6 inhibitor. It is used for research purposes to study cancer cell growth, specifically by inhibiting cell proliferation and arresting the cell cycle at the G1 phase. This compound suppresses retinoblastoma tumor suppressor protein (Rb) phosphorylation and E2 factor (E2F)-regulated gene expression.
- Orally active and selective CDK4/6 inhibitor.
- Inhibits cancer cell growth by arresting the cell cycle at G1 phase.
- Suppresses retinoblastoma tumor suppressor protein (Rb) phosphorylation at S780.
- Triggers apoptosis in MV4-11 and MDA-MB-453 cells.
- Potently inhibits FLT3 and MYLK4.
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