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Medchemexpress LLC Cdk7-in-21 | 2766124-39-2 | C33H36FN9O2 | 1 MG
Supplier: Medchemexpress LLC HY1532781MG
Q901 (CDK7-IN-21) is a selective and potent CDK7 inhibitor with an IC50 of 10 nM. It disrupts MYC and E2F-driven cancer, such as colon cancer and lung cancer, by inhibiting CDK7.
- Selective and potent CDK7 inhibitor (IC50 of 10 nM)
- Disrupts MYC and E2F-driven cancer progression
- Inhibits proliferation of MCF-7 breast cancer cells
- Induces DNA damage accumulation in MCF-7 cells
- Synergistically inhibits proliferation of various cancer cells when combined with other therapies
- Inhibits tumor growth in HCT116 colon cancer xenograft models
- Enhances tumor growth inhibition in combination with relevant drugs
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