Medchemexpress LLC Cdk9-in-7 | 2369981-71-3 | 98.1% | 547.71 | C29H37N7O2S | 5MG

Supplier:  Medchemexpress LLC HY1262515MG

CDK9-IN-7 is a selective, potent, orally active small-molecule inhibitor of CDK9/cyclin T for research use. It exhibits strong biochemical potency (IC50 = 11 nM), preferential selectivity versus other CDKs, and has demonstrated antitumor activity in preclinical non-small-cell lung cancer models by inducing apoptosis, causing G2 cell-cycle arrest, and reducing cancer stemness.

• Selective CDK9/cyclin T inhibition with reduced activity against CDK4 and CDK6
• Potent biochemical activity (IC50 = 11 nM) for target engagement studies
• Demonstrated antitumor effects in NSCLC models, including apoptosis and G2 arrest
• Suitable for in vitro and in vivo research, including oral administration studies
• Available as powder and as a 10 mM solution in DMSO for screening
• High purity (~98.1%) for reliable experimental results

Catalog No. 50-002-34938