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Abcam CDPPB, positive allosteric modulator for mGlu5, 10MG

Supplier:  Abcam AB12036310MG

Encompass_Preferred

MW 364.4 Da, Purity >98%. Potent, selective, positive allosteric modulator for mGlu5. In CHO cells expressing mGlu5 receptors, potentiates threshold responses to glutamate in fluorometric Ca2+ assays more than 7-fold (EC50 approximately 27 nM). Acts as mGlu5 agonist at higher concentrations. Brain penetrant and antipsychotic *in vivo*.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-7654


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