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Medchemexpress LLC Cecropin A (TFA) | 80451-04-3 | >98% | 4003.78 (free base) | 10 MG
SDP

Catalog No. 5000422126
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Cecropin A TFA is a linear 37-residue antimicrobial polypeptide isolated from Hyalaphora cecropia pupae. It exhibits anti-bacterial, anti-inflammatory, and anti-cancer activity.

  • Induces cytotoxicity on HL-60 cells in a dose-dependent manner and induces apoptosis independent of caspase activation.
  • Shows good antibacterial activity against multidrug-resistant Gram-negative bacteria such as *A. baumanii* and multidrug-resistant *P. aeruginosa*.
  • Exhibits anti-inflammatory activities, effectively suppressing the expression of mTNF-a, mIL-1β, and mMIP-2 mRNA.
  • Slightly inhibits the expression of mMIP-1 mRNA.
  • Effectively inhibits LPS-induced phosphorylation of ERK, JNK, p38 MAPK, and reduces the expression of COX-2.

Catalog No. 50-004-22126 Supplier Medchemexpress LLC Supplier No. HYP1539A10MG
May include imposed supplier surcharges.
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Cecropin A TFA is a linear 37-residue antimicrobial polypeptide isolated from Hyalaphora cecropia pupae. It exhibits anti-bacterial, anti-inflammatory, and anti-cancer activity.

  • Induces cytotoxicity on HL-60 cells in a dose-dependent manner and induces apoptosis independent of caspase activation.
  • Shows good antibacterial activity against multidrug-resistant Gram-negative bacteria such as *A. baumanii* and multidrug-resistant *P. aeruginosa*.
  • Exhibits anti-inflammatory activities, effectively suppressing the expression of mTNF-a, mIL-1β, and mMIP-2 mRNA.
  • Slightly inhibits the expression of mMIP-1 mRNA.
  • Effectively inhibits LPS-induced phosphorylation of ERK, JNK, p38 MAPK, and reduces the expression of COX-2.

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