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Medchemexpress LLC Cediranib maleate | 857036-77-2 | 99.95% | 10 MM * 1 ML
SDP

Supplier:  Medchemexpress LLC HY1304910MM/1ML

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Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor. It effectively inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, and c-Kit, making it a valuable tool for angiogenesis and cancer research.

  • Potent inhibition of VEGF-stimulated proliferation and KDR phosphorylation in human umbilical vein endothelial cells.
  • Reduces vessel area, length, and branching in in vitro vessel sprouting models.
  • Ablates experimental angiogenesis and inhibits endochondral ossification in vivo.
  • Inhibits growth of various human tumor xenografts in athymic mice.
  • Induces microvessel density reduction and vascular regression in tumors.
  • Actively investigated in clinical trials for various cancer types.

Catalog No. 50-003-40810


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