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Abcam Ceefourin™ 1, MRP4 inhibitor, 1MG
Supplier: Abcam AB1451441MG
MW 294.4 Da, Purity >99%. Highly selective multidrug resistance protein 4 (MRP4) inhibitor (IC50 = 1.5 µM). Blocked transport of MRP4 substrates 6-Mercaptopurine, SN 38, cAMP, D-Luciferin and E217βG. No detectable effect on MRP4 homologs MRP1, 2, 3 or 5, and related transporters P-gp and ABCG2 *in vitro*. Low cellular toxicity, and high microsomal and acid stability. Chemically distinctive to Ceefourin™ 2 (ab145145).
The product is subject to the following: Abcam Restricted Use Statement
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