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Medchemexpress LLC Cefotetan | 69712-56-7 | 50 MG
Supplier: Medchemexpress LLC HYN667050MG
Cefotetan is a binding agent targeting human Raf1 kinase inhibitor protein (hRKIP). It binds to hRKIP, relieving its inhibition of the Ras/Raf1/MEK/ERK signaling pathway and enhancing ERK phosphorylation. It also acts as a broad-spectrum antibacterial agent disrupting bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs).
- Investigates diseases linked to dysregulated Ras/Raf1/MEK/ERK signaling pathways by enhancing ERK phosphorylation.
- Effective against various bacterial infections: bone, skin, urinary tract, and lower respiratory tract.
- Active against Gram-positive (Staphylococci, Streptococci) and Gram-negative bacteria (Enterobacter, Haemophilus influenzae).
- Highly stable against plasmid- and chromosome-mediated β-lactamases.
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