Medchemexpress LLC Ceftiofur hydrochloride | 103980-44-5 | 98.4% | C19H18ClN5O7S3 | 1 ML

Supplier:  Medchemexpress LLC HYB002610MM/1ML

Ceftiofur hydrochloride is a potent cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs). It exerts bactericidal effects by inhibiting bacterial cell wall peptidoglycan synthesis, leading to cell lysis. Additionally, it possesses anti-inflammatory properties, inhibiting NF-κB and MAPKs, which reduces the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. This compound has been shown to improve survival rates in endotoxemia models.

• Targets bacterial penicillin-binding proteins (PBPs)
• Inhibits bacterial cell wall peptidoglycan synthesis
• Induces bacterial cell lysis
• Reduces secretion of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6)
• Inhibits phosphorylation of ERK, JNK, and p38
• Blocks nuclear translocation of NF-κB p65
• Improves survival in endotoxemia models
• Cited in 4 scientific publications

Catalog No. 50-004-32492