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Cayman Chemical Cel-Based asy Buffer B10 25mL

Supplier: Cayman Chemical 70197225 ML

An inhibitor of DPP-4 (IC50 0.015 UM) selective for DPP-4 over DPP-8 and DPP-9 (IC50s >50 UM for both) increases plasma levels of GLP-1 and insulin in rats at 10 mg/kg reduces blood glucose levels in an oral glucose tolerance test in mice at 3 mg/kg decreases blood glucose levels alone and in combination with metformin in an oral glucose tolerance test in a mouse model of high-fat diet-induced obesity at 0.1 mg/kg
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