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AdipoGen Celastrol

Supplier: AdipoGen AGCN20460M010
Chemical. CAS 34157-83-0. Formula C29H38O4. MW 450.6. Isolated from Tripterygium wilfordii. Anti-obesity agent. Potent leptin sensitizer. Antioxidant. Potent lipid peroxidation inhibitor. NADPH oxidases NOX1, 2, 4 and 5 inhibitor. Anti-inflammatory. NF-kappaB inhibitor. HSP90 inhibitor and HSP70 inducer. Anticancer agent. Apoptosis and autophagy inducer. Inhibits PI3K/Akt signaling pathways. Anti-metastatic and anti-angiogenic compound. Reduces VEGFR expression and inhibits HIF-1alpha pathway. Topoisomerase II inhibitor. 20S proteasome chymotrypsin-like activity inhibitor. Potential antiviral and anti-Alzheimers agent.
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