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Medchemexpress LLC Centanafadine hydrochloride | 923981-14-0 | 99.6% | 245.75 | 25 MG
Supplier: Medchemexpress LLC 25MGHY16736A
Centanafadine hydrochloride is a dual norepinephrine (NE) and dopamine (DA) transporter inhibitor, which also inhibits the serotonin transporter. It has IC50s of 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporters, respectively. This product is for research use only and not sold to patients.
- Inhibits monoamine reuptake in cloned cell lines.
- Significantly increases NE and DA concentrations in rat prefrontal cortex.
- Decreases immobility in mouse tail suspension test of depression.
- Inhibits locomotor hyperactivity in juvenile rats with 6-hydroxydopamine lesions (an animal model for ADHD).
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