Cephalexin hydrate, 97+%

Description

Cephalexin hydrate, cefalexin hydrate, CAS # 23325-78-2, is a first-generation cephalosporin antibiotic from the beta-lactam family. | CAS: 15686-71-2 | C16H20ClN3O5S | 401.862 g/mol

Cephalexin is a cephalosporin antibiotic used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis. Cephalexin disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cephalexin antibiotics mimic the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Cephalexin hydrate is the hydrate of the cephalosporin antibiotic, cephalexin

• Cephalexin is a beta-lactam antibiotic that inhibits bacterial growth and division

• Cephalexin binds to penicillin-binding protein and inhibits cell wall synthesis

Application

• Cephalexin works best on gram-positive microbes

• Useful for immunology research, particularly on antibiotic allergies and cross-reactivity

Specifications

Chemical Identifiers

• CAS: 15686-71-2
• Molecular Formula: C16H20ClN3O5S
• Molecular Weight (g/mol): 401.862
• MDL Number: MFCD00167148
• InChI Key: YHJDZIQOCSDIQU-OEDJVVDHSA-N
• PubChem CID: 57515946
• IUPAC Name: (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydron;chloride;hydrate
• SMILES: [H+].CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=CC=C3)N)SC1)C(=O)O.O.[Cl-]

• Type: Cephalexin Hydrate
• Physical Form: Powder
• Color: White
• Quantity: 5 g
• Beilstein: 965503
• Merck Index: 141974
• Solubility Information: Soluble in DMSO and Methanol.
• Formula Weight: 347.39 (Anhydrous)
• Percent Purity: ≥97%
• Chemical Name or Material: Cephalexin hydrate

Safety and Handling

Hazard Category	Respiratory sensitisation (category 1), Skin sensitisation (category 1)
Hazard Statement	May cause allergy or asthma symptoms or breathing difficulties if inhaled, May cause an allergic skin reaction
EINECSNumber	239-773-6
RTECSNumber	XI0350000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only