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Cayman Chemical CephalosporIn CzInc 10mg
SDP

Supplier:  Cayman Chemical 3326210 MG

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An AMPA receptor antagonist (Ki 0.084 M in a radioligand binding assay using rat brain membranes) selective for AMPA over kainate NMDA-sensitive glutamate and strychnine-insensitive glycine receptors (Kis 2.2 100 and 37 M respectively) intrastriatal administration inhibits AMPA-induced decreases in ChAT activity in rat striatum ex vivo inhibits audiogenic seizures in susceptible DBA/2 mice with a minimum effective dose of 3 mg/kg i.p. intravenous infusion reduces infarct size in a rat model of focal cerebral ischemia induced by thrombotic MCAO in rats at 20 mg/kg per hour for 4 hours

Catalog No. 50-294-9970


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