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Medchemexpress LLC Ceramide 3 | 34354-88-6 | >98.0% | C36H73NO4 | 1 MG
Supplier: Medchemexpress LLC HY1415821MG
Ceramide 3 (also known as N-Stearoyl phytosphingosine or C18 Phytoceramide) is a bioactive sphingolipid naturally occurring in the stratum corneum of organisms like Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. It is structurally composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain.
- Regulates apoptosis, cell differentiation, and proliferation of smooth muscle cells
- Inhibits the mitochondrial respiratory chain
- Suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue
- Formulations are used as skin protectants in cosmetics
- Helps reduce water loss and prevent epidermal dehydration and irritation
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