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Cayman Chemical CerdulatInIb 10mg
Supplier: Cayman Chemical 2007610 MG
A dual inhibitor of Syk and JAK (IC50s = 32, 12, 6, 8, and 0.5 nM for Syk, JAK1, JAK2, JAK3, and TYK2, respectively); exhibits nanomolar inhibition of other kinases; inhibits JAK1/3-mediated STAT phosphorylation with IC50 values ranging from 0.16 to 1 μM; antitumor activity with IC50 values ranging from 0.05 to 2.1 μM against DLBCL tumor cell lines
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