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Enzo Life Sciences Cerulenin (25mg). CAS: 17397-89-6
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Supplier:  Enzo Life Sciences BMLG2370025

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Antibiotic. Fatty acid synthase (FAS) inhibitor reported to bind in equimolar ratio to β-keto-acyl-ACP synthase (KAS; IC50=1.5µM), thus inhibiting protein acylation at concentrations of 45-134 µM. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes). Alternative name: 2,3-Epoxy-4-oxo-7,10-dodecadienamide. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (>10mg/ml) or 100% ethanol (>10mg/ml). Long Term Storage: -20°C.

Catalog No. 50-201-0870


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