Cerulenin, 98%, Thermo Scientific Chemicals

Description

Has antibiotic and antifungal properties; inhibits fatty acid and steroid biosynthesis

Cerulenin is used as an antifungal antibiotic that inhibits sterol and fatty acids biosynthesis. Cerulenin induces apoptosis in tumor cell lines. It can be a useful biochemical tool with applications for the study of metabolism and function of fatty acids in the bacterial cell membrane and in yeast. An extensive review including the properties, uses, mechanism of action and structure has been reported.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cerulenin is used as an antifungal antibiotic that inhibits sterol and fatty acids biosynthesis. Cerulenin induces apoptosis in tumor cell lines. It can be a useful biochemical tool with applications for the study of metabolism and function of fatty acids in the bacterial cell membrane and in yeast. An extensive review including the properties, uses, mechanism of action and structure has been reported.

Solubility
Soluble in acetone at 20mg/ml. Also soluble in ethanol, benzene, chloroform, or ethyl acetate.

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers..

Specifications

Chemical Identifiers

• CAS: 17397-89-6
• Molecular Formula: C12H17NO3
• Molecular Weight (g/mol): 223.272
• MDL Number: MFCD00077686
• InChI Key: GVEZIHKRYBHEFX-NQQPLRFYSA-N
• Synonym: (2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide
• PubChem CID: 5282054
• ChEBI: CHEBI:171741
• IUPAC Name: (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide
• SMILES: CC=CCC=CCCC(=O)C1C(O1)C(=O)N

• Type: Cerulenin
• Physical Form: Powder
• Color: White to Yellow
• Quantity: 10 mg
• Beilstein: 4140423
• Merck Index: 14,2004
• Solubility Information: Soluble in acetone at 20mg/ml; Also soluble in ethanol,benzene,chloroform,or ethyl acetate.
• Formula Weight: 223.27
• Percent Purity: 98%
• Chemical Name or Material: Cerulenin

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
EINECSNumber	241-424-8
RTECSNumber	JR1670000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only