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Apexbio Technology LLC Cetirizine DiHCl 83881-52-1 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B15475.1
Cetirizine dihydrochloride (CAS 83881-52-1) is a second-generation antihistamine structurally related to hydroxyzine It functions as a racemic selective inverse agonist of the histamine H1 receptor thereby attenuating histamine-mediated cellular responses Owing to its low penetration of the blood-brain barrier cetirizine exhibits reduced sedative effects compared to first-generation antihistamines This compound is widely utilized in biomedical research to investigate allergic pathways histaminergic signaling and the pharmacological modulation of conditions such as seasonal allergic rhinitis angioedema and urticaria
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