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Medchemexpress LLC Cevimeline hydrochloride hemihydrate | 153504-70-2 | >98% | C10H17NOS.HCl.1/2H2O | 1 ML
SDP

Catalog No. 5000434034
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Cevimeline hydrochloride hemihydrate is a quinuclidine derivative of acetylcholine and a selective muscarinic M1 and M3 receptor agonist. This orally active compound stimulates secretion by the salivary glands, making it a candidate therapeutic drug for xerostomia, including in Sjogren's syndrome. It is also known to cross the blood-brain barrier.

  • Selective muscarinic M1 and M3 receptor agonist
  • Stimulates salivary gland secretion
  • Can be used as a sialogogue for xerostomia
  • Crosses the blood-brain barrier
  • Targets mAChR
  • Affects gastrointestinal, urinary, and reproductive systems
  • Increases intracellular Ca2+ concentration in parotid cells (In vitro)
  • Induces salivation and increases blood flow in the parotid gland (In vivo)

Catalog No. 50-004-34034 Supplier Medchemexpress LLC Supplier No. HY76772B10MM/1ML
May include imposed supplier surcharges.
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Cevimeline hydrochloride hemihydrate is a quinuclidine derivative of acetylcholine and a selective muscarinic M1 and M3 receptor agonist. This orally active compound stimulates secretion by the salivary glands, making it a candidate therapeutic drug for xerostomia, including in Sjogren's syndrome. It is also known to cross the blood-brain barrier.

  • Selective muscarinic M1 and M3 receptor agonist
  • Stimulates salivary gland secretion
  • Can be used as a sialogogue for xerostomia
  • Crosses the blood-brain barrier
  • Targets mAChR
  • Affects gastrointestinal, urinary, and reproductive systems
  • Increases intracellular Ca2+ concentration in parotid cells (In vitro)
  • Induces salivation and increases blood flow in the parotid gland (In vivo)

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