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Medchemexpress LLC Cevimeline hydrochloride hemihydrate | 153504-70-2 | >98% | C10H17NOS.HCl.1/2H2O | 1 ML
Supplier: Medchemexpress LLC HY76772B10MM/1ML
Cevimeline hydrochloride hemihydrate is a quinuclidine derivative of acetylcholine and a selective muscarinic M1 and M3 receptor agonist. This orally active compound stimulates secretion by the salivary glands, making it a candidate therapeutic drug for xerostomia, including in Sjogren's syndrome. It is also known to cross the blood-brain barrier.
- Selective muscarinic M1 and M3 receptor agonist
- Stimulates salivary gland secretion
- Can be used as a sialogogue for xerostomia
- Crosses the blood-brain barrier
- Targets mAChR
- Affects gastrointestinal, urinary, and reproductive systems
- Increases intracellular Ca2+ concentration in parotid cells (In vitro)
- Induces salivation and increases blood flow in the parotid gland (In vivo)
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