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Sigma Aldrich Fine Chemicals Biosciences CfTM 633 succinimidyl este
Supplier: Sigma Aldrich Fine Chemicals Biosciences SCJ46000391UMOL
far-red fluorescent dyes offer the advantage of ultra sensitive detection because background signal due to autofluorescence in most biological samples is minimal in this spectral region. for many years the cyanine dye Cy(R)5 has been the dye of choice for such detection. More recently Alexa fluor(R) 647 has been developed as a better alternative by having brighter fluorescence and higher photostability. Despite the improvement Alexa fluor(R) 647 still lacks sufficient photostability required for many demanding applications. On the other hand while Alexa fluor(R) 633 is photostable its fluorescence on proteins is very weak. In fact it has been a challenging task for dye chemists to develop a far-red fluorescent dye that is both highly fluorescent and photostable for protein and nucleic acid labeling. Using new chemistry scientists at Biotium have successfully developed a series of far-red and near-IR dyes to overcome these challenges. With its absorption peak at 630 nm Cf(TM)633
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