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Medchemexpress LLC CFTR(inh)-172 | 307510-92-5 | 99.8% | 409.40 | 1 ML

Supplier: Medchemexpress LLC HY1667110MM/1ML
CFTR(inh)-172 is a potent and selective blocker of the CFTR chloride channel, reversibly inhibiting CFTR short-circuit current with a Ki of 300 nM. It is intended for research use only.
- Potent and selective CFTR chloride channel blocker.
- Reversibly inhibits CFTR short-circuit current in less than 2 minutes.
- Nontoxic to FRT cells at concentrations up to 100 μM.
- Reduces open probability by > 90% in CFTR channels.
- Significantly reduces cholera toxin-induced fluid secretion in mouse models.
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