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Medchemexpress LLC cGAMP (diammonium) | 96.63% | 708.47 | 25 MG
Supplier: Medchemexpress LLC 25MGHY110385A
cGAMP (Cyclic GMP-AMP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. It activates stimulator of interferon genes (STING), which leads to a signaling cascade that produces type I interferons and other immune mediators.
- Functions naturally in metazoans
- Responds to cytosolic DNA by triggering interferon production
- Activates STING, initiating a signaling cascade for type I interferons and other immune mediators
- Promotes the antigen-specific proliferation capacity of spleen cells in mice
- Directly activates murine and human dendritic cells in vitro
- Induces an antiviral state and secretion of type I IFNs
- Promotes antigen-specific cytokine production by spleen cells of immunized mice
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