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CGK 733, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Originally defined as a selective inhibitor of ATR and ATM kinases. Induces cell death in prematurely senescent breast cancer cells. Decreases p21CIP1 levels in premature senescent MCF-7 and HCT-116 cells; also exhibits antiproliferative activity in a range of cancer cell lines. Blocks camptothecin -induced p53 phosphorylation and protects cells from camptothecin-induced apoptosis.
Specifications
Quantity | 50 mg |
Formula Weight | 555.84 |
Percent Purity | >98% |
Chemical Name or Material | CGK 733 |
Safety and Handling
Recommended Storage : Store at +4°C